GO:0006099 biological_process tricarboxylic acid cycle
| PAG Title | GO:0006099 biological_process tricarboxylic acid cycle |
| PAG ID | TAX016129 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. |
| Species | Homo sapiens |
| nCoCo Score | 3,462 |
| Base PAG ID | TAX016129 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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